Development of the genetically encoded red fluorescent Ca2+ indicator R-CaMP1.07
نویسندگان
چکیده
منابع مشابه
An Improved Genetically Encoded Red Fluorescent Ca2+ Indicator for Detecting Optically Evoked Action Potentials
Genetically encoded Ca(2+) indicators (GECIs) are powerful tools to image activities of defined cell populations. Here, we developed an improved red fluorescent GECI, termed R-CaMP1.07, by mutagenizing R-GECO1. In HeLa cell assays, R-CaMP1.07 exhibited a 1.5-2-fold greater fluorescence response compared to R-GECO1. In hippocampal pyramidal neurons, R-CaMP1.07 detected Ca(2+) transients triggere...
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ژورنال
عنوان ژورنال: Folia Pharmacologica Japonica
سال: 2013
ISSN: 0015-5691,1347-8397
DOI: 10.1254/fpj.141.175